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  • Writer's pictureJess Hope


Known for its peppery and spicy aroma, caryophyllene is found in cloves, peppermint, cinnamon, basil, hops, oregano and more. It is also found in the cannabis plant and has many potential medical benefits. This terpene is also known for its anti-inflammatory effects.

Fun Facts

Caryophyllene is the only known terpene to act as a cannabinoid as well. This terpene activates the endocannabinoid system and can reduce inflammation. Caryophyllene is one of the first cannabis derived compounds other than THC, CBD, CBN that binds directly to the endocannabinoid system.

Potential medical benefits

  • Anti-Inflammatory benefits. Caryophyllene is known for its potential anti-inflammatory properties. This means it can possibly help reduce swelling, inflammation and reduce pain. Many topical makers will seek out a strain high in caryophyllene to curate topicals.

  • Caryophyllene has the possibility of reducing anxiety in cannabis consumers.

  • Users report that using strains high in this terpene results in relaxation and reduced stress levels.

  • In combination with other terpenes, Caryophyllene can help with sleep. A study published in 2012 showed that mice treated with an essential oil that had the essence of Caryophyllene in it, experienced an increased sleep time. (Sedative Effects of Essential Oils Obtained from Baccharis Uncinella, n.d.)

  • In addition to all these potential benefits, Caryophyllene is also known to act as an antifungal and antimicrobial

Strains high in Caryophyllene;

  • OG Kush

  • GSC

  • Sour Diesel

  • Original Glue

  • White Widow

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